Article
Enhancer-derived long non-coding RNAs CCAT1 and CCAT2 at rs6983267 has limited predictability for early stage colorectal carcinoma metastasis.
Scientific reports - 11 Jan 2021
Thean Lai Fun, Blöcker Christopher, Li Hui Hua, Lo Michelle, Wong Michelle, Tang Choong Leong, Tan Emile K W, Rozen Steven G, Cheah Peh Yean
Abstract excerpt
Up-regulation of long non-coding RNAs (lncRNAs), colon-cancer associated transcript (CCAT) 1 and 2, was associated with worse prognosis in colorectal cancer (CRC). Nevertheless, their role in predicting metastasis in early-stage CRC is unclear. We measured the expression of CCAT1, CCAT2 and their oncotarget, c-Myc, in 150 matched mucosa-tumour samples of early-stage microsatellite-stable Chinese CRC patients with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
