Article
Long non-coding RNA CCAT2 promotes cholangiocarcinoma cells migration and invasion by induction of epithelial-to-mesenchymal transition.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Mar 2018
Xu Yi, Yao Yue, Qin Wei, Zhong Xiangyu, Jiang Xingming, Cui Yunfu
Abstract excerpt
Cholangiocarcinoma (CCA) is one of the most aggressive malignancies in humans. Emerging evidence has indicated that abnormally expressed long non-coding RNAs (lncRNAs) could conduce to tumorigenesis and progression. Specifically, colon cancer-associated transcript 2 (CCAT2) has been reported to be overexpressed in several carcinomas. However, its clinical significance and functional roles in CCA is still unknown....
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