Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2–specific CD8+ T cell responses in convalescent COVID-19 individuals

11 Jan 2021

Abstract excerpt

Characterization of the T cell response in individuals who recover from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is critical to understanding its contribution to protective immunity. A multiplexed peptide-MHC tetramer approach was used to screen 408 SARS-CoV-2 candidate epitopes for CD8+ T cell recognition in a cross-sectional sample of 30 coronavirus disease 2019 convalescent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33427749
DOI: 10.1172/jci145476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2–specific CD8+ T cell responses in convalescent COVID-19 individualsPMID 33427749Read ↗

Phenotypes and Functions of SARS-CoV-2-Reactive T CellsSemantic proximity Read ↗

COVID-19 Patients Form Memory CD8+ T Cells that Recognize a Small Set of Shared Immunodominant Epitopes in SARS-CoV-2Semantic proximity Read ↗

COVID-19 Patients Form Memory CD8+ T Cells that Recognize a Small Set of Shared Immunodominant Epitopes in SARS-CoV-2Semantic proximity Read ↗

Comprehensive longitudinal profiling of SARS-CoV-2-specific CD8 <sup>+</sup> T-cells reveal strong functional impairment and recognition bias as markers for disease severitySemantic proximity Read ↗

Parallel detection of SARS‐CoV ‐2 epitopes reveals dynamic immunodominance profiles of CD8 + T memory cells in convalescent COVID ‐19 donorsSemantic proximity Read ↗

Leveraging T-cell receptor – epitope recognition models to disentangle unique and cross-reactive T-cell response to SARS-CoV-2 during COVID-19 progression/resolutionSemantic proximity Read ↗

Identification and characterization of a SARS-CoV-2 specific CD8+ T cell response with immunodominant features.Semantic proximity Read ↗

Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19Semantic proximity Read ↗

CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity.Semantic proximity Read ↗

Rapid, simplified whole blood-based multiparameter assay to quantify and phenotype SARS-CoV-2-specific T-cells.Semantic proximity Read ↗

Recruitment of highly functional SARS-CoV-2-specific CD8 <sup>+</sup> T cell receptors mediating cytotoxicity of virus-infected target cells in non-severe COVID-19Semantic proximity Read ↗

The T cell immune response against SARS-CoV-2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.