Article
Rapid, simplified whole blood-based multiparameter assay to quantify and phenotype SARS-CoV-2-specific T-cells.
The European respiratory journal - 1 Jan 2022
Riou Catherine, Schäfer Georgia, du Bruyn Elsa, Goliath Rene T, Stek Cari, Mou Huihui, Hung Deli, Wilkinson Katalin A, Wilkinson Robert J
Abstract excerpt
BACKGROUND: Rapid tests to evaluate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T-cell responses are urgently needed to decipher protective immunity and aid monitoring vaccine-induced immunity. METHODS: Using a rapid whole blood assay requiring a minimal amount of blood, we measured qualitatively and quantitatively SARS-CoV-2-specific CD4 T-cell responses in 31 healthcare workers using...
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