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Article

Genetic profile of adult T-cell leukemia/lymphoma in Okinawa: Association with prognosis, ethnicity, and HTLV-1 strains.

Cancer science - 1 Mar 2021

Sakihama Shugo, Morichika Kazuho, Saito Rumiko, Miyara Megumi, Miyagi Takashi, Hayashi Masaki, Uchihara Junnosuke, Tomoyose Takeaki, Ohshiro Kazuiku, Nakayama Shingo, Nakachi Sawako, Morishima Satoko, Sakai Kazuko, Nishio Kazuto, Masuzaki Hiroaki, Fukushima Takuya, Karube Kennosuke

Abstract excerpt

Genetic alterations in adult T-cell leukemia/lymphoma (ATLL), a T-cell malignancy associated with HTLV-1, and their clinical impacts, especially from the perspective of viral strains, are not fully elucidated. We employed targeted next-generation sequencing and single nucleotide polymorphism array for 89 patients with ATLL in Okinawa, the southernmost islands in Japan, where the frequency of HTLV-1 tax subgroup-A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33426772
DOI: 10.1111/cas.14806
PMCID: PMC7935801

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