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Article

KHDRBS3 promotes multi-drug resistance and anchorage-independent growth in colorectal cancer.

Cancer science - 1 Mar 2021

Ukai Shoichi, Sakamoto Naoya, Taniyama Daiki, Harada Kenji, Honma Ririno, Maruyama Ryota, Naka Kazuhito, Hinoi Takao, Takakura Yuji, Shimizu Wataru, Ohdan Hideki, Yasui Wataru

Abstract excerpt

5-Fluorouracil (5-FU) is one of the most frequently used pharmacological agents in the treatment of colorectal cancer (CRC). Resistance to chemotherapy is a major cause of treatment failure of CRC, and it is a well known fact that cancer stem cells play a significant role in the acquisition of drug resistance. In this study, we focused on the KHDRBS3 gene that encodes KH RNA Binding Domain Containing, Signal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33423358
DOI: 10.1111/cas.14805
PMCID: PMC7935809

Genes

KHDRBS3
KRAS
CD44

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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