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Article

FKBP3 mediates oxaliplatin resistance in colorectal cancer cells by regulating HDAC2 expression

2 Aug 2019

Abstract excerpt

Colorectal cancer (CRC), a commonly occurring malignant tumor in the gastrointestinal tract, is the third leading cause of cancer‑related deaths worldwide. FK506‑binding proteins (FKBPs) comprise an immunophilin family that are involved in the carcinogenesis, progression and chemoresistance of cancers, including CRC. FKBP3 (also known as FKBP25) is a nuclear protein that is a member of the FKBP family and is...

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PMID: 31524278
DOI: 10.3892/or.2019.7259

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