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Inhibition of autophagy by 3‐methyladenine restricts murine cytomegalovirus replication

15 Jan 2021

Abstract excerpt

Cytomegalovirus (CMV) induced autophagy affects virus replication and survival of the infected cells. The purpose of this study was to investigate the role of autophagy inhibition by 3-methyladenine (3-MA) on murine cytomegalovirus (MCMV) replication and whether it is associated with caspase-3 dependent apoptosis. The eyecup isolated from adult C57BL/6J mice (6-8 weeks old) and mouse embryo fibroblast cells...

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PMID: 33421149
DOI: 10.1002/jmv.26787

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