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Autophagy Negatively Regulates Transmissible Gastroenteritis Virus Replication

31 Mar 2016

Abstract excerpt

Autophagy is an evolutionarily ancient pathway that has been shown to be important in the innate immune defense against several viruses. However, little is known about the regulatory role of autophagy in transmissible gastroenteritis virus (TGEV) replication. In this study, we found that TGEV infection increased the number of autophagosome-like double- and single-membrane vesicles in the cytoplasm of host cells,...

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PMID: 27029407
DOI: 10.1038/srep23864

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