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Article

PRSS55 plays an important role in the structural differentiation and energy metabolism of sperm and is required for male fertility in mice.

Journal of cellular and molecular medicine - 1 Feb 2021

Zhu Feng, Li Wen, Zhou Xinli, Chen Xu, Zheng Meimei, Cui Yiqiang, Liu Xiaofei, Guo Xuejiang, Zhu Hui

Abstract excerpt

Orderly and stage-specifically expressed proteins are essential for spermatogenesis, and proteases play a key role in protein activation and function. The present study aimed to investigate serine protease 55 (PRSS55), which was reported to play a role in sperm-uterotubal junction (UTJ) migration and sperm-zona pellucida (ZP) binding. We found that PRSS55 was specifically expressed in testicular spermatids and...

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Source

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Identifiers

PMID: 33417308
DOI: 10.1111/jcmm.16116
PMCID: PMC7882947

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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