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Article

PRSS55 is a novel potential causative gene for human male infertility.

Reproductive biomedicine online - 1 Sept 2022

Liu Man, Jiang Chuan, Zhang Xueguang, Zhang Guohui, Liu Mohan, Zheng Rui, Yang Yihong, Shen Ying

Abstract excerpt

RESEARCH QUESTION: Testis-specific PRSS55 is a chymotrypsin-like serine protease that is highly conserved among mammalian species. The essential role of Prss55 in mouse male fertility has been established. What is the role of PRSS55 in human reproduction? DESIGN: Whole exome sequencing was used to identify the genetic cause in an infertile male with teratozoospermia. Papanicolaou staining, scanning electron...

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Identifiers

PMID: 35821214
DOI: 10.1016/j.rbmo.2022.05.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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