Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heme as Possible Contributing Factor in the Evolvement of Shiga-Toxin Escherichia coli Induced Hemolytic-Uremic Syndrome.

Frontiers in immunology - 1 Jan 2020

Wijnsma Kioa L, Veissi Susan T, de Wijs Sem, van der Velden Thea, Volokhina Elena B, Wagener Frank A D T G, van de Kar Nicole C A J, van den Heuvel L P

Abstract excerpt

Shiga-toxin (Stx)-producing Escherichia coli hemolytic-uremic syndrome (STEC-HUS) is one of the most common causes of acute kidney injury in children. Stx-mediated endothelial injury initiates the cascade leading to thrombotic microangiopathy (TMA), still the exact pathogenesis remains elusive. Interestingly, there is wide variability in clinical presentation and outcome. One explanation for this could be the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Susceptibility
Share to Endothelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heme Oxygenase-1

Share to Hemolytic-Uremic Syndrome

Share to Reactive Oxygen Species

Share to Shiga-Toxigenic Escherichia coli

Share to Thromboplastin

Source

Open in PubMed Open full text

Identifiers

PMID: 33414780
DOI: 10.3389/fimmu.2020.547406
PMCID: PMC7783363

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heme as Possible Contributing Factor in the Evolvement of Shiga-Toxin Escherichia coli Induced Hemolytic-Uremic Syndrome.PMID 33414780Read ↗

Advances in our understanding of the pathogenesis of hemolytic uremic syndromes.Semantic proximity Read ↗

Pathogenesis and prognosis of thrombotic microangiopathy.Semantic proximity Read ↗

Shiga toxin-associated hemolytic uremic syndrome: advances in pathogenesis and therapeutics.Semantic proximity Read ↗

New Aspects in the Pathogenesis of Enteropathic Hemolytic Uremic SyndromeSemantic proximity Read ↗

The hemolytic uremic syndromes.Semantic proximity Read ↗

Molecular and functional analysis of Shiga toxin–induced response patterns in human vascular endothelial cellsSemantic proximity Read ↗

Pathogenesis of Shiga Toxin-Associated Hemolytic Uremic SyndromeSemantic proximity Read ↗

Pathophysiology of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.Semantic proximity Read ↗

Distinct renal pathology and a chemotactic phenotype after enterohemorrhagic Escherichia coli shiga toxins in non-human primate models of hemolytic uremic syndrome.Semantic proximity Read ↗

Genetic Susceptibility to Postdiarrheal Hemolytic-Uremic Syndrome After Shiga Toxin-Producing Escherichia coli Infection: A Centers for Disease Control and Prevention FoodNet Study.Semantic proximity Read ↗

Soluble CD40 Iigand and Oxidative Response Are Reciprocally Stimulated during Shiga Toxin-Associated Hemolytic Uremic SyndromeSemantic proximity Read ↗

Specific Interaction of Escherichia coli 0157:H7-Derived Shiga-like Toxin II with Human Renal Endothelial CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.