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Article

Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics.

Breast cancer research : BCR - 30 Jan 2015

McCart Reed Amy E, Kutasovic Jamie R, Lakhani Sunil R, Simpson Peter T

Abstract excerpt

Invasive lobular carcinoma of the breast is the most common 'special' morphological subtype of breast cancer, comprising up to 15% of all cases. Tumours are generally of a good prognostic phenotype, being low histological grade and low mitotic index, hormone receptor positive and HER2, p53 and basal marker negative, and with a generally good response to endocrine therapy. Despite this, clinicians face countless...

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Identifiers

PMID: 25849106
DOI: 10.1186/s13058-015-0519-x
PMCID: PMC4310190

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