Article
The CRE1 carbon catabolite repressor of the fungus Trichoderma reesei: a master regulator of carbon assimilation.
BMC genomics - 27 May 2011
Portnoy Thomas, Margeot Antoine, Linke Rita, Atanasova Lea, Fekete Erzsébet, Sándor Erzsébet, Hartl Lukas, Karaffa Levente, Druzhinina Irina S, Seiboth Bernhard, Le Crom Stéphane, Kubicek Christian P
Abstract excerpt
BACKGROUND: The identification and characterization of the transcriptional regulatory networks governing the physiology and adaptation of microbial cells is a key step in understanding their behaviour. One such wide-domain regulatory circuit, essential to all cells, is carbon catabolite repression (CCR): it allows the cell to prefer some carbon sources, whose assimilation is of high nutritional value, over less...
Topics
- Binding Sites
- Carbon
- Fungal Proteins
- Gene Knockout Techniques
- Genome, Fungal
- Glucose
- Hypocreales
- Mutation
- Phenotype
- Protein Structure, Tertiary
- Repressor Proteins
- Up-Regulation