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Article

Warfarin and vitamin K intake in the era of pharmacogenetics.

British journal of clinical pharmacology - 1 Aug 2010

Lurie Yael, Loebstein Ronen, Kurnik Daniel, Almog Shlomo, Halkin Hillel

Abstract excerpt

The considerable variability in the warfarin dose-response relationship between individuals, is explained mainly by genetic variation in its major metabolic (CYP2C9) and target (VKORC1) enzymes. Despite the predominance of pharmacogenetics, environmental factors also affect the pharmacokinetics a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20653669
DOI: 10.1111/j.1365-2125.2010.03672.x
PMCID: PMC2911546

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20653669-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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