Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancer

4 Jan 2021

Abstract excerpt

Intratumoural heterogeneity (ITH) contributes to local recurrence following radiotherapy in prostate cancer. Recent studies also show that ecological interactions between heterogeneous tumour cell populations can lead to resistance in chemotherapy. Here, we evaluated whether interactions between heterogenous populations could impact growth and response to radiotherapy in prostate cancer. Using mixed 3D cultures...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Mathematical Biology Tumor Growth
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33398023
DOI: 10.1038/s42003-020-01529-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancerPMID 33398023Read ↗

Mathematical model of heterogeneous cancer growth with an autocrine signalling pathway.Semantic proximity Read ↗

Impacts of competition and phenotypic plasticity on the viability of adaptive therapySemantic proximity Read ↗

A resource-based mechanistic framework for castration-resistant prostate cancer (CRPC)Semantic proximity Read ↗

Eco‐oncology: Applying ecological principles to understand and manage cancerSemantic proximity Read ↗

Impacts of competition and phenotypic plasticity on the viability of adaptive therapy.Semantic proximity Read ↗

Integrating Mathematical Modeling with High-Throughput Imaging Explains How Polyploid Populations Behave in Nutrient-Sparse Environments.Semantic proximity Read ↗

Aggregation Effects and Population-Based Dynamics as a Source of Therapy Resistance in CancerSemantic proximity Read ↗

Invasion of homogeneous and polyploid populations in nutrient-limiting environmentsSemantic proximity Read ↗

Stochastic modelling of prostate progenitor architectureSemantic proximity Read ↗

Niche Inheritance: A Cooperative Pathway to Enhance Cancer Cell Fitness Through Ecosystem EngineeringSemantic proximity Read ↗

A Strategy to Delay the Development of Cisplatin Resistance by Maintaining a Certain Amount of Cisplatin-Sensitive CellsSemantic proximity Read ↗

Modeling the effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.