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Article

Validation in a Brazilian population of gene markers of periodontitis previously investigated by GWAS and bioinformatic studies.

Journal of periodontology - 1 May 2021

Cirelli Thamiris, Nepomuceno Rafael, Orrico Silvana R P, Rossa Carlos, Cirelli Joni A, North Kari E, Graff Mariaelisa, Barros Silvana P, Scarel-Caminaga Raquel M

Abstract excerpt

BACKGROUND: Bioinformatic tools and genome-wide association studies (GWAS) have led to comprehensive identification of single nucleotide polymorphisms (SNPs) associated with periodontitis in diverse populations. Here we aimed to detect and validate the association of seven SNPs as genetic markers of susceptibility to periodontitis in a Brazilian population. METHODS: This case-control study assessed complete...

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Identifiers

PMID: 32909266
DOI: 10.1002/JPER.20-0126

Genes

IL37
NCR2
NPY
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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