Article
High-resolution HLA allele and haplotype frequencies of the Saudi Arabian population based on 45,457 individuals and corresponding stem cell donor matching probabilities.
Human immunology - 1 Feb 2021
Alfraih Feras, Alawwami Moheeb, Aljurf Mahmoud, Alhumaidan Hind, Alsaedi Hawazen, El Fakih Riad, Alotaibi Bander, Rasheed Walid, Bernas Stefanie N, Massalski Carolin, Heidl Annett, Sauter Jürgen, Lange Vinzenz, Schmidt Alexander H
Abstract excerpt
We estimated HLA allele and haplotype frequencies of the Saudi Arabian population from a sample of 45,457 registered stem cell donors. The most frequent HLA alleles were A*02:01g (18.5%), C*06:02g (16.1%), B*51:01g (14.1%), DRB1*07:01g (16.2%), DQB1*02:01g (30.5%), and DPB1*04:01g (33.6%). The most frequent 5-locus haplotypes were A*02:05g~C*06:02g~B*50:01g~DRB1*07:01g~DQB1*02:01g (1.73%),...
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