Article
Analysis of mitochondrial DNA sequence variants in patients with polycystic ovary syndrome.
Archives of gynecology and obstetrics - 1 Sept 2012
Zhuo Guangchao, Ding Yu, Feng Guofang, Yu Lin, Jiang Yan
Abstract excerpt
PURPOSE: To understand the role of mitochondrial DNA (mtDNA) mutations in patients with polycystic ovary syndrome (PCOS). METHODS: A total of 57 women with PCOS and 38 controls were recruited in this study, mutational analysis of mitochondrial genome was performed using polymerase chain reaction and under a direct sequence analysis. RESULTS: Sequence characterization of mitochondrial genome showed a distinct set...
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