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Mitochondrial DNA 4977 bp Deletion in Peripheral Blood Is Associated With Polycystic Ovary Syndrome

8 Jul 2021

Abstract excerpt

Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder worldwide. We aimed to examine the associations of two mitochondrial DNA (mtDNA) biomarkers in the peripheral blood, mtDNA copy number (CN), and mtDNA 4977 deletion rate (DR), with PCOS in a clinical setting. Methods We performed a study involving 263 women with PCOS and 326 age-matched controls between June 2015 and June 2019. The mtDNA...

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PMID: 34305813
DOI: 10.3389/fendo.2021.675581

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