Article
What chickens might tell us about the MHC class II system.
Current opinion in immunology - 1 Jun 2017
Parker Aimée, Kaufman Jim
Abstract excerpt
Almost all knowledge about the structure and function of MHC class II molecules outside of mammals comes from work with chickens. Most of the genes implicated in the class II system are present in chickens, so it is likely that the machinery of antigen processing and peptide-loading is similar to mammals. However, there is only one isotype (lineage) of classical class II genes, with one monomorphic DR-like BLA...
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