Article
Systems Immunology Analysis Reveals an Immunomodulatory Effect of Snail-p53 Binding on Neutrophil- and T Cell-Mediated Immunity in KRAS Mutant Non-Small Cell Lung Cancer.
Frontiers in immunology - 1 Jan 2020
Hammoudeh Sarah Musa, Venkatachalam Thenmozhi, Ansari Abdul Wahid, Bendardaf Riyad, Hamid Qutayba, Rahmani Mohamed, Hamoudi Rifat
Abstract excerpt
Immunomodulation and chronic inflammation are important mechanisms utilized by cancer cells to evade the immune defense and promote tumor progression. Therefore, various efforts were focused on the development of approaches to reprogram the immune response to increase the immune detection of cancer cells and enhance patient response to various types of therapy. A number of regulatory proteins were investigated...
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