Article

KRAS mutation promotes immune escape of lung adenocarcinoma via ZNF24/SLC7A5/PD-L1 axis

2025-04-01

Abstract excerpt

<title>Abstract</title> <p>Background The imbalance of immune checkpoint molecules leads to immune escape of tumor cells. It has been established that KRAS mutation plays a key role in regulating PD-L1 expression of lung adenocarcinoma. However, the specific mechanism by which KRAS mutation regulates PD-L1 expression still needs further been clarified. Methods The relationship of KRAS mutation and ZNF24, SLC7A5...

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Literature Corpus work: 85507ec1-1c15-5e27-88d1-2a1deaeb1eb9
DOI: 10.21203/rs.3.rs-5052649/v1

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