Article
Utility of incorporating next-generation sequencing (NGS) in an Asian non-small cell lung cancer (NSCLC) population: Incremental yield of actionable alterations and cost-effectiveness analysis.
Lung cancer (Amsterdam, Netherlands) - 1 Jan 2020
Tan Aaron C, Lai Gillianne G Y, Tan Gek San, Poon Shou Yu, Doble Brett, Lim Tse Hui, Aung Zaw Win, Takano Angela, Tan Wan Ling, Ang Mei-Kim, Tan Bien Soo, Devanand Anantham, Too Chow Wei, Gogna Apoorva, Ong Boon-Hean, Koh Tina P T, Kanesvaran Ravindran, Ng Quan Sing, Jain Amit, Rajasekaran Tanujaa, Lim Alvin S T, Lim Wan Teck, Toh Chee Keong, Tan Eng-Huat, Lim Tony Kiat Hon, Tan Daniel S W
Abstract excerpt
OBJECTIVES: There is an expanding list of therapeutically relevant biomarkers for non-small cell lung cancer (NSCLC), and molecular profiling at diagnosis is paramount. Tissue attrition in scaling traditional single biomarker assays from small biopsies is an increasingly encountered problem. We sought to compare the performance of targeted next-generation sequencing (NGS) panels with traditional assays and...
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