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Article

Personalized cancer vaccination in head and neck cancer.

Cancer science - 1 Mar 2021

Shibata Hirofumi, Zhou Liye, Xu Na, Egloff Ann Marie, Uppaluri Ravindra

Abstract excerpt

Cancer is characterized by an accumulation of somatic mutations that represent a source of neoantigens for targeting by antigen-specific T cells. Head and neck squamous cell carcinoma (HNSCC) has a relatively high mutation burden across all cancer types, and cellular immunity to neoantigens likely plays a key role in HNSCC clinical outcomes. Immune checkpoint inhibitors (CPIs) have brought new treatment options...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33368875
DOI: 10.1111/cas.14784
PMCID: PMC7935792

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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