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Article

The head and neck cancer genome in the era of immunotherapy.

Oral oncology - 1 Jan 2021

Wijetunga N Ari, Yu Yao, Morris Luc G, Lee Nancy, Riaz Nadeem

Abstract excerpt

The recent success of immunotherapy in head and neck squamous cell carcinoma (HNSCC) has necessitated a new perspective on the cancer genome. Here we review recent advances in the carcinogenesis and molecular genetics of HNSCC with an eye on their implications for cancer immunity. Newer sequencing technologies have recently facilitated dissection of the complex interaction between the HPV virus, tumor, host...

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Carcinogenesis
Immunotherapy
Papillomaviridae
Papillomavirus Infections
Reactive Oxygen Species

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Squamous Cell Carcinoma of Head and Neck

Tumor Microenvironment

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PMID: 33197752
DOI: 10.1016/j.oraloncology.2020.105040

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