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Article

Frequent DYRK2 gene amplification in micropapillary element of lung adenocarcinoma - an implication in progression in EGFR-mutated lung adenocarcinoma.

Histology and histopathology - 1 Mar 2021

Koike Chihiro, Okudela Koji, Matsumura Mai, Mitsui Hideaki, Suzuki Takehisa, Arai Hiromasa, Kataoka Toshiaki, Ishikawa Yoshihiro, Umeda Shigeaki, Tateishi Yoko, Ohashi Kenichi

Abstract excerpt

The present study aimed to discern the molecular alterations involved in the progression of EGFR-mutated lung adenocarcinoma (LADC). We previously demonstrated that the micropapillary (mPAP) element is the most important histological factor for assessing malignant grades in LADCs. Therefore, mPAP and other elements were separately collected from three cases of EGFR-mutated LADC using laser capture microdissection...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33368138
DOI: 10.14670/HH-18-294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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