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Micropapillary Lung Adenocarcinoma

15 Apr 2009

Abstract excerpt

Micropapillary lung adenocarcinoma (MPA) has been reported as an aggressive variant of adenocarcinoma, frequently manifesting at high stage with a poor prognosis. We analyzed the clinical and molecular profile of 15 primary MPAs for K-ras, EGFR, and BRAF mutations and performed fluorescence in situ hybridization for EGFR amplification. In our study, 11 (73%) of 15 MPAs harbored mutually exclusive mutations: 5...

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PMID: 19369630
DOI: 10.1309/ajcpbs85vjeobpdo

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