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Article

Micropapillary: A component more likely to harbour heterogeneous EGFR mutations in lung adenocarcinomas.

Scientific reports - 5 Apr 2016

Cai Yi-Ran, Dong Yu-Jie, Wu Hong-Bo, Liu Zi-Chen, Zhou Li-Juan, Su Dan, Chen Xue-Jing, Zhang Li, Zhao Ying-Li

Abstract excerpt

The micropapillary (MP) subtype has recently been established to be a distinct marker of poor prognosis in lung adenocarcinomas (LACs). According to the 2015 WHO classification system, LAC constituents are required to be precisely reported. T790M mutation and an insertion in exon 20 (E20ins) are associated with EGFR-TKI resistance. A total of 211 LAC patients were involved in this study, and EGFR mutations were...

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Identifiers

PMID: 27046167
DOI: 10.1038/srep23755
PMCID: PMC4820702

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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