Article
A Histopathological Feature of EGFR-Mutated Lung Adenocarcinomas with Highly Malignant Potential - An Implication of Micropapillary Element.
PloS one - 1 Jan 2016
Matsumura Mai, Okudela Koji, Kojima Yoko, Umeda Shigeaki, Tateishi Yoko, Sekine Akimasa, Arai Hiromasa, Woo Tetsukan, Tajiri Michihiko, Ohashi Kenichi
Abstract excerpt
The purpose of this study was to define histological features determining the malignant potential of EGFR-mutated lung adenocarcinoma (LADC). Surgically resected tumors (EGFR-mutated LADCs with (21) and without (79) lymph node metastasis and EGFR wild-type LADCs with (26) and without (108) lymph node metastasis) and biopsy samples from inoperably advanced tumors (EGFR-mutated LADCs (78) and EGFR wild-type LADCs...
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