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Article

Systematically Characterizing A-to-I RNA Editing Neoantigens in Cancer

10 Dec 2020

Abstract excerpt

A-to-I RNA editing can contribute to the transcriptomic and proteomic diversity of many diseases including cancer. It has been reported that peptides generated from RNA editing could be naturally presented by human leukocyte antigen (HLA) molecules and elicit CD8+ T cell activation. However, a systematical characterization of A-to-I RNA editing neoantigens in cancer is still lacking. Here, an integrated...

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PMID: 33363023
DOI: 10.3389/fonc.2020.593989

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