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Coding SNPs in hsa-miR-1343-3p and hsa-miR-6783-3p target sites of CYP2C19 modulates clopidogrel response in individuals with cardiovascular diseases.

Life sciences - 15 Mar 2020

Sharma Anu Radha, Vohra Manik, Shukla Vaibhav, Guddattu Vasudeva, Razak Uk Abdul, Shetty Ranjan, Umakanth Shashikiran, Satyamoorthy Kapaettu, Rai Padmalatha S

Abstract excerpt

AIMS: To investigate the impact of microRNA target SNPs (mirSNPs) and their interaction with miRNAs on important drug-metabolizing enzymes, transporters and target genes for prediction of clopidogrel drug response in cardiovascular disease individuals. MAIN METHODS: A prospective cross-sectional study was conducted on 292 individuals undergoing clopidogrel drug therapy. All the enrolled participants were...

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PMID: 32001263
DOI: 10.1016/j.lfs.2020.117364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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