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Article

Comprehensive Bioinformatics Analysis of Key Methyltransferases and Demethylases for Histone Lysines in Hepatocellular Carcinoma.

Technology in cancer research & treatment - 1 Jan 2000

Zheng Yang, Tang Lili, Chen Guojiang, Liu Ziling

Abstract excerpt

BACKGROUND & AIMS: Methylation of lysines on histones, controlled by various methyltransferases and demethylases, is an important component of epigenetic modifications, and abnormal regulation of such enzymes serves as common events in hepatocellular carcinoma. We determined to identify important methyltransferases and demethylases that might regulate the development of hepatocellular carcinoma by bioinformatics....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33355042
DOI: 10.1177/1533033820983284
PMCID: PMC7871294

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