Article

Development and validation of epigenetic signature predict survival for patients with laryngeal squamous cell carcinoma

2020-04-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Epigenetic alterations, such as DNA methylation patterns, yield an important role in the initiation, progression and prognosis of laryngeal squamous cell carcinoma (LSCC). We performed a genome-wide integrated analysis of methylation and the transcriptome to establish epigenetic signature to improve the accuracy of survival prediction and optimize therapeutic st...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 79711840-cbaa-5515-bfe7-eb03174d3f47
DOI: 10.21203/rs.3.rs-24974/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Development and validation of epigenetic signature predict survival for patients with laryngeal squamous cell carcinomaDOI 10.21203/rs.3.rs-24974/v1Read

Identification and validation of methylation-driven genes prognostic signature for recurrence of laryngeal squamous cell carcinoma by integrated bioinformatics analysisSemantic proximity Read

Molecular Subtypes Based on DNA Methylation Predict Prognosis in Lung Squamous Cell CarcinomaSemantic proximity Read

Molecular subtypes based on DNA methylation predict prognosis in lung squamous cell carcinomaSemantic proximity Read

A 8-gene-methylation-based Signature for Head and Neck Squamous Cell Carcinoma PrognosisSemantic proximity Read

A Novel Four-CpG Prognostic Risk Score Model Predicts Survival and Guides Therapy in Patients with Head and Neck Squamous Cell CarcinomaSemantic proximity Read

A prognostic 11-DNA methylation signature for lung squamous cell carcinomaSemantic proximity Read

A Methylation-based nomogram for predicting survival in patients with lung adenocarcinomaSemantic proximity Read

Comprehensive Analysis of Epigenetic Alternations of MicroRNA and DNA Methylation Contribute to Gene Expression and Prognosis in Lung Squamous Cell CarcinomaSemantic proximity Read

Identification of DNA methylation-driven genes in esophageal squamous cell carcinoma: a study based on The Cancer Genome AtlasSemantic proximity Read

Genome-wide DNA methylation profiling reveals novel epigenetic signatures in squamous cell lung cancerSemantic proximity Read

Targeted bisulfite sequencing identified a panel of DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC)Semantic proximity Read

A risk score system based on DNA methylation levels and a nomogram survival model for lung squamous cell carcinomaSemantic proximity Read