Implantation failure and embryo loss contribute to subfertility in female mice mutant for chromatin remodeler Cecr2†.

Abstract excerpt

Defects in the maternal reproductive system that result in early pregnancy loss are important causes of human female infertility. A wide variety of biological processes are involved in implantation and establishment of a successful pregnancy. Although chromatin remodelers have been shown to play an important role in many biological processes, our understanding of the role of chromatin remodelers in female...

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