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Article

E2f4 and E2f5 are essential for the development of the male reproductive system

17 Jan 2016

Abstract excerpt

The E2F transcription factors are primarily implicated in the regulation of entry and exit from the cell cycle. However, in vivo studies have established additional roles for E2Fs during organ development and homeostasis. With the goal of addressing the intestinal requirements of E2f4 and E2f5, we crossed mice carrying Vil-cre, E2f4 conditional and E2f5 germline alleles. E2f4 deletion had no detectable effect on...

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Identifiers

PMID: 26825228
DOI: 10.1080/15384101.2015.1121350

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