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Article

Defects at the Posttranscriptional Level Account for the Low TCRζ Chain Expression Detected in Gastric Cancer Independently of Caspase-3 Activity.

Journal of immunology research - 1 Jan 2020

Aguinaga-Barrilero Ana, Castro-Sánchez Patricia, Juárez Ignacio, Gutiérrez-Calvo Alberto, Rodríguez-Pérez Noelia, Lopez Adela, Gómez Remedios, Martin-Villa José M

Abstract excerpt

BACKGROUND: Reduced TCRζ chain surface has been reported in T cells from patients with different inflammatory conditions and cancer. However, the causes of this diminished expression in cancer remain elusive. METHODS: T cell-enriched populations of blood or tissue (tumoral and nontumoral) origin from 44 patients with gastric adenocarcinoma and 33 healthy subjects were obtained. Samples were subjected to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Antigen, T-Cell

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Source

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Identifiers

PMID: 33354577
DOI: 10.1155/2020/1039458
PMCID: PMC7737443

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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