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Coronavirus genomes carry the signatures of their habitats

22 Dec 2020

Abstract excerpt

Coronaviruses such as SARS-CoV-2 regularly infect host tissues that express antiviral proteins (AVPs) in abundance. Understanding how they evolve to adapt or evade host immune responses is important in the effort to control the spread of infection. Two AVPs that may shape viral genomes are the zinc finger antiviral protein (ZAP) and the apolipoprotein B mRNA editing enzyme-catalytic polypeptide-like 3 (APOBEC3)....

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PMID: 33351847
DOI: 10.1371/journal.pone.0244025

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