Article
[Analysis of carrying clinically significant allelic variants of TPMT and DPYD genes associated with the response to drug therapy in cancer practice among 9 ethnic groups of the Russian Federation].
Terapevticheskii arkhiv - 3 Sept 2020
Mirzaev K B, Fedorinov D S, Akmalova K A, Abdullaev S P, Kachanova A A, Sozaeva Z A, Grishina E A, Shuev G N, Kitaeva E Y, Shprakh V V, Suleymanov S S, Bolieva L Z, Sozaeva M S, Zhuchkova S M, Gimaldinova N E, Sidukova E E, Burashnikova I S, Shikaleva A A, Zabudskaya K G, Sychev D A
Abstract excerpt
AIM: To study the peculiarities of carrying clinically significant allelic variants of TPMT and DPYD genes associated with the response to drug therapy in cancer practice among 9 ethnic groups of the Russian Federation. MATERIALS AND METHODS: The study included 1446 conditionally healthy volunteers from 9 ethnic groups. Carriage of polymorphic TPMT and DPYD gene markers was detected by the Real-Time PCR...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.