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Article

Comprehensive assessment of PD-L1 and PD-L2 dysregulation in gastrointestinal cancers.

Epigenomics - 1 Dec 2020

Zhao Qijie, Guo Jinan, Zhao Yueshui, Shen Jing, Kaboli Parham Jabbarzadeh, Xiang Shixin, Du Fukuan, Wu Xu, Li Mingxing, Wan Lin, Li Xiang, Wen Qinglian, Li Jing, Zou Chang, Xiao Zhangang

Abstract excerpt

Background:PD-L1 and PD-L2 are ligands of PD-1. Their overexpression has been reported in different cancers. However, the underlying mechanism of PD-L1 and PD-L2 dysregulation and their related signaling pathways are still unclear in gastrointestinal cancers. Materials & methods: The expression of PD-L1 and PD-L2 were studied in The Cancer Genome Atlas and Genotype-Tissue Expression databases. The gene and...

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Identifiers

PMID: 33337915
DOI: 10.2217/epi-2020-0093

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