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Developments in the Treatment of Leber Hereditary Optic Neuropathy.

Current neurology and neuroscience reports - 1 Dec 2022

Chen Benson S, Yu-Wai-Man Patrick, Newman Nancy J

Abstract excerpt

PURPOSEOF REVIEW: To outline the current landscape of treatments for Leber hereditary optic neuropathy (LHON) along the therapeutic delivery pipeline, exploring the mechanisms of action and evidence for these therapeutic approaches. RECENT FINDINGS: Treatments for LHON can be broadly classified as either mutation-specific or mutation-independent. Mutation-specific therapies aim to correct the underlying mutation...

Topics

Humans
Optic Atrophy, Hereditary, Leber
DNA, Mitochondrial
Retinal Ganglion Cells
Mitochondria
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36414808
DOI: 10.1007/s11910-022-01246-y
PMCID: PMC9750907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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