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Article

Full exome sequencing of 11 families with Hidradenitis suppurativa

18 Dec 2020

Abstract excerpt

BACKGROUND: Hidradenitis suppurativa (HS) is not a well-studied or easily treated disease. Genetic information is essential for advances in the understanding and treatment of HS. This study aims to examine mutations in the gamma-secretase complex, the Notch signalling pathway and to perform a Mendelian analysis of genetic variants that segregated with disease in a full exome sequencing of 11 families with HS....

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PMID: 33336462
DOI: 10.1111/jdv.17095

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