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Article

γ-Secretase Genetics of Hidradenitis Suppurativa: A Systematic Literature Review.

Dermatology (Basel, Switzerland) - 1 Jan 2021

Wang Zhongshuai, Yan Yan, Wang Baoxi

Abstract excerpt

BACKGROUND: Acne inversa/hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory disease of the skin that can significantly affect patients' quality of life. The etiology and pathogenesis of HS are unclear and gene mutations might play a role. SUMMARY: The primary focus of the review is on aggregating the gene mutations reported, summarizing the structure of γ-secretase and analyzing and speculating...

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Identifiers

PMID: 33333507
DOI: 10.1159/000512455
PMCID: PMC8491499

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