Article
Heritability curves: A local measure of heritability in family models.
Statistics in medicine - 15 Mar 2021
Berentsen Geir D, Azzolini Francesca, Skaug Hans J, Lie Rolv T, Gjessing Håkon K
Abstract excerpt
Classical heritability models for family data split the phenotype variance into genetic and environmental components. For instance, the ACE model in twin studies assumes the phenotype variance decomposes as a2 + c2 + e2 , representing (additive) genetic effects, common (shared) environment, and residual environment, respectively. However, for some phenotypes it is biologically plausible that the genetic and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
