Article
A robust and unified framework for estimating heritability in twin studies using generalized estimating equations.
Statistics in medicine - 30 Nov 2020
Arbet Jaron, McGue Matt, Basu Saonli
Abstract excerpt
The 'heritability' of a phenotype measures the proportion of trait variance due to genetic factors in a population. In the past 50 years, studies with monozygotic and dizygotic twins have estimated heritability for 17,804 traits;1 thus twin studies are popular for estimating heritability. Researchers are often interested in estimating heritability for non-normally distributed outcomes such as binary, counts,...
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