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Article

CTLA-4 +49A/G Polymorphism Increases the Susceptibility to Bladder Cancer in Chinese Han Participants: A Case-Control Study.

Disease markers - 1 Jan 2020

Mao Fei, Niu Xiao-Bing, Gu Shuo, Ji Lu, Wei Bing-Jian, Wang Heng-Bing

Abstract excerpt

Cytotoxic T cell antigen-4 (CTLA-4) is reportedly involved in the development of bladder cancer (BC). This research was designed to address the potential link between the +49A/G polymorphism in CTLA-4 gene and BC susceptibility. In total, 355 BC cases and 435 match controls from Chinese Han individuals were included eventually. The PCR-RFLR method was utilized to screen for this polymorphism. The +49A/G...

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Identifiers

PMID: 33335608
DOI: 10.1155/2020/8143158
PMCID: PMC7723475

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