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Article

HIV-1 cure strategies: why CRISPR?

17 Dec 2020

Abstract excerpt

INTRODUCTION: Antiretroviral therapy (ART) has transformed prognoses for HIV-1-infected individuals but requires lifelong adherence to prevent viral resurgence. Targeted elimination or permanent deactivation of the latently infected reservoir harboring integrated proviral DNA, which drives viral rebound, is a major focus of HIV-1 research. AREAS COVERED: This review covers the current approaches to developing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33331178
DOI: 10.1080/14712598.2021.1865302

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