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Tackling HIV Persistence: Pharmacological versus CRISPR-Based Shock Strategies

29 Mar 2018

Abstract excerpt

Jan Svoboda studied aspects of viral latency, in particular with respect to disease induction by avian RNA tumor viruses, which were later renamed as part of the extended retrovirus family. The course of retroviral pathogenesis is intrinsically linked to their unique property of integrating the DNA copy of the retroviral genome into that of the host cell, thus forming the provirus. Retroviral latency has recently...

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PMID: 29596334
DOI: 10.3390/v10040157

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