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Article

Quantitative multiplex profiling of the complement system to diagnose complement‐mediated diseases

1 Jan 2020

Abstract excerpt

OBJECTIVES: Complement deficiencies are difficult to diagnose because of the variability of symptoms and the complexity of the diagnostic process. Here, we applied a novel 'complementomics' approach to study the impact of various complement deficiencies on circulating complement levels. METHODS: Using a quantitative multiplex mass spectrometry assay, we analysed 44 peptides to profile 34 complement proteins...

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PMID: 33318796
DOI: 10.1002/cti2.1225

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