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Complement‐targeted therapeutics: An emerging field enabled by academic drug discovery

9 Feb 2023

Abstract excerpt

Within a short few years, the number of complement inhibitors that are either approved for therapeutic application or evaluated in late-stage clinical trials has expanded remarkably. The sudden emergence of this target area in the pipelines of many biotech start-ups and even large pharmaceutical companies appears even more surprising when considering that the involvement of the complement system in various...

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PMID: 36755352
DOI: 10.1002/ajh.26875

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